Entity Details

Name RAB8A
ID P61006
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAP3K7RAB8AThr72
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AGQERFRtITTAYYRphosphorylation
up-regulates activity		32227113SIGNOR-260266
STK24RAB8AThr72
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AGQERFRtITTAYYRphosphorylation
up-regulates activity		32227113SIGNOR-260265
PINK1RAB8ASer111
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RNIEEHAsADVEKMIphosphorylation
down-regulates activity		31361120SIGNOR-260268
LRRK2RAB8AThr72
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AGQERFRtITTAYYRphosphorylation
up-regulates activity		32227113SIGNOR-260267
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAP3K7phosphorylation
up-regulates
→
RAB8A
PThr72		phosphorylation
up-regulates
→		RAB8A32227113SIGNOR-260266
STK24phosphorylation
up-regulates
→
RAB8A
PThr72		phosphorylation
up-regulates
→		RAB8A32227113SIGNOR-260265
PINK1phosphorylation
up-regulates
→
RAB8A
PSer111		phosphorylation
down-regulates
⊣		RAB8A31361120SIGNOR-260268
LRRK2phosphorylation
up-regulates
→
RAB8A
PThr72		phosphorylation
up-regulates
→		RAB8A32227113SIGNOR-260267
Regulator Mechanism/Effect Target SIGNOR-ID
MAP3K7phosphorylation
→
up-regulates activity 		RAB8ASIGNOR-260266
STK24phosphorylation
→
up-regulates activity 		RAB8ASIGNOR-260265
PINK1phosphorylation
→
down-regulates activity 		RAB8ASIGNOR-260268
LRRK2phosphorylation
→
up-regulates activity 		RAB8ASIGNOR-260267