| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | RAB5B | Thr6 | tARPNGQP | phosphorylation up-regulates activity | 25605758 | SIGNOR-276873 |
| CDK1 | RAB5B | Ser123 | KELQRQAsPSIVIAL | phosphorylation unknown | 10403367 | SIGNOR-69233 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | phosphorylation up-regulates → | RAB5B PThr6 | phosphorylation up-regulates → | RAB5B | 25605758 | SIGNOR-276873 |
| CDK1 | phosphorylation up-regulates → | RAB5B PSer123 | phosphorylation down-regulates ⊣ | RAB5B | 10403367 | SIGNOR-69233 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LRRK2 | phosphorylation → up-regulates activity | RAB5B | SIGNOR-276873 |
| CDK1 | phosphorylation → unknown | RAB5B | SIGNOR-69233 |
