| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | RAB10 | Thr73 | AGQERFHtITTSYYR | phosphorylation down-regulates activity | 26824392 | SIGNOR-261277 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | phosphorylation up-regulates → | RAB10 PThr73 | phosphorylation down-regulates ⊣ | RAB10 | 26824392 | SIGNOR-261277 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LRRK2 | phosphorylation → down-regulates activity | RAB10 | SIGNOR-261277 |
