| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCG | STXBP1 | Ser306 | VSQEVTRsLKDFSSS | phosphorylation unknown | 12519779 | SIGNOR-249184 |
| PRKCG | STXBP1 | Ser313 | SLKDFSSsKRMNTGE | phosphorylation down-regulates activity | 12519779 | SIGNOR-249187 |
| PRKCA | STXBP1 | Ser306 | VSQEVTRsLKDFSSS | phosphorylation unknown | 12519779 | SIGNOR-249182 |
| PRKCB | STXBP1 | Ser306 | VSQEVTRsLKDFSSS | phosphorylation unknown | 12519779 | SIGNOR-249183 |
| PRKCE | STXBP1 | – | phosphorylation down-regulates quantity | 29946239 | SIGNOR-279479 | |
| PRKCB | STXBP1 | Ser313 | SLKDFSSsKRMNTGE | phosphorylation down-regulates activity | 12519779 | SIGNOR-249186 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCG | phosphorylation up-regulates → | STXBP1 PSer306 | phosphorylation down-regulates ⊣ | STXBP1 | 12519779 | SIGNOR-249184 |
| PRKCG | phosphorylation up-regulates → | STXBP1 PSer313 | phosphorylation down-regulates ⊣ | STXBP1 | 12519779 | SIGNOR-249187 |
| PRKCA | phosphorylation up-regulates → | STXBP1 PSer306 | phosphorylation down-regulates ⊣ | STXBP1 | 12519779 | SIGNOR-249182 |
| PRKCB | phosphorylation up-regulates → | STXBP1 PSer306 | phosphorylation down-regulates ⊣ | STXBP1 | 12519779 | SIGNOR-249183 |
| PRKCB | phosphorylation up-regulates → | STXBP1 PSer313 | phosphorylation down-regulates ⊣ | STXBP1 | 12519779 | SIGNOR-249186 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCG | phosphorylation → unknown | STXBP1 | SIGNOR-249184 |
| PRKCG | phosphorylation → down-regulates activity | STXBP1 | SIGNOR-249187 |
| PRKCA | phosphorylation → unknown | STXBP1 | SIGNOR-249182 |
| PRKCB | phosphorylation → unknown | STXBP1 | SIGNOR-249183 |
| PRKCE | phosphorylation → down-regulates quantity | STXBP1 | SIGNOR-279479 |
| PRKCB | phosphorylation → down-regulates activity | STXBP1 | SIGNOR-249186 |
