| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | STXBP1 | Ser313 | SLKDFSSsKRMNTGE | phosphorylation down-regulates activity | 12519779 | SIGNOR-249186 |
| PRKCG | STXBP1 | Ser313 | SLKDFSSsKRMNTGE | phosphorylation down-regulates activity | 12519779 | SIGNOR-249187 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | phosphorylation up-regulates → | STXBP1 PSer313 | phosphorylation down-regulates ⊣ | STXBP1 | 12519779 | SIGNOR-249186 |
| PRKCG | phosphorylation up-regulates → | STXBP1 PSer313 | phosphorylation down-regulates ⊣ | STXBP1 | 12519779 | SIGNOR-249187 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCB | phosphorylation → down-regulates activity | STXBP1 | SIGNOR-249186 |
| PRKCG | phosphorylation → down-regulates activity | STXBP1 | SIGNOR-249187 |