Entity Details

Name HNRNPK
ID P61978
Role substrate
Enzymatic Domains
KH 1 42-104
PROSITE-ProRule
KH 2 144-209
PROSITE-ProRule
KH 3 387-451
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCDHNRNPKSer302GRGGRGGsRARNLPLphosphorylation
unknown
10329716SIGNOR-260877
JNKHNRNPKSer216 ILDLISEsPIKGRAQphosphorylation
up-regulates
11259409SIGNOR-105758
MAPK8HNRNPKSer216 ILDLISEsPIKGRAQphosphorylation
up-regulates
11259409SIGNOR-105766
SRCHNRNPKTyr236FYDETYDyGGFTMMFphosphorylation
down-regulates
12052863SIGNOR-88911
SRCHNRNPKTyr225IKGRAQPyDPNFYDEphosphorylation
down-regulates
12052863SIGNOR-88899
SRCHNRNPKTyr380 YAGGRGSyGDLGGPIphosphorylation
down-regulates
12052863SIGNOR-88915
SRCHNRNPKTyr230QPYDPNFyDETYDYGphosphorylation
down-regulates
12052863SIGNOR-88903
MAPK8HNRNPKSer216 ILDLISEsPIKGRAQphosphorylation
up-regulates activity
11259409SIGNOR-105247
MAPK10HNRNPKSer284 RRDYDDMsPRRGPPPphosphorylation
down-regulates activity
11231586SIGNOR-250082
JNKHNRNPKSer353DSAIDTWsPSEWQMAphosphorylation
up-regulates
11259409SIGNOR-105762
MAPK3HNRNPKSer284 RRDYDDMsPRRGPPPphosphorylation
down-regulates
16564677SIGNOR-145375
MAPK10HNRNPKSer216 ILDLISEsPIKGRAQphosphorylation
up-regulates activity
11259409SIGNOR-250081
PRKCDHNRNPKSer302GRGGRGGsRARNLPLphosphorylation
down-regulates
10329716SIGNOR-67515
SRCHNRNPKTyr234PNFYDETyDYGGFTMphosphorylation
down-regulates
12052863SIGNOR-88907
MAPK8HNRNPKSer353DSAIDTWsPSEWQMAphosphorylation
up-regulates activity
11259409SIGNOR-105251
ERK1/2HNRNPKSer353DSAIDTWsPSEWQMAphosphorylation
up-regulates
11259409SIGNOR-105754
SRCHNRNPKTyr72IKALRTDyNASVSVPphosphorylation
down-regulates
12052863SIGNOR-88919
MAPK3HNRNPKSer284 RRDYDDMsPRRGPPPphosphorylation
down-regulates activity
11231586SIGNOR-105238
MAPK8HNRNPKSer353DSAIDTWsPSEWQMAphosphorylation
up-regulates
11259409SIGNOR-105770
MAPK10HNRNPKSer353DSAIDTWsPSEWQMAphosphorylation
up-regulates activity
11259409SIGNOR-250083
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCDphosphorylation
up-regulates
→
HNRNPK
PSer302
phosphorylation
down-regulates
⊣
HNRNPK10329716SIGNOR-260877
JNKphosphorylation
up-regulates
→
HNRNPK
PSer216
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-105758
MAPK8phosphorylation
up-regulates
→
HNRNPK
PSer216
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-105766
SRCphosphorylation
up-regulates
→
HNRNPK
PTyr236
phosphorylation
down-regulates
⊣
HNRNPK12052863SIGNOR-88911
SRCphosphorylation
up-regulates
→
HNRNPK
PTyr225
phosphorylation
down-regulates
⊣
HNRNPK12052863SIGNOR-88899
SRCphosphorylation
up-regulates
→
HNRNPK
PTyr380
phosphorylation
down-regulates
⊣
HNRNPK12052863SIGNOR-88915
SRCphosphorylation
up-regulates
→
HNRNPK
PTyr230
phosphorylation
down-regulates
⊣
HNRNPK12052863SIGNOR-88903
MAPK8phosphorylation
up-regulates
→
HNRNPK
PSer216
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-105247
MAPK10phosphorylation
up-regulates
→
HNRNPK
PSer284
phosphorylation
down-regulates
⊣
HNRNPK11231586SIGNOR-250082
JNKphosphorylation
up-regulates
→
HNRNPK
PSer353
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-105762
MAPK3phosphorylation
up-regulates
→
HNRNPK
PSer284
phosphorylation
down-regulates
⊣
HNRNPK16564677SIGNOR-145375
MAPK10phosphorylation
up-regulates
→
HNRNPK
PSer216
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-250081
PRKCDphosphorylation
up-regulates
→
HNRNPK
PSer302
phosphorylation
down-regulates
⊣
HNRNPK10329716SIGNOR-67515
SRCphosphorylation
up-regulates
→
HNRNPK
PTyr234
phosphorylation
down-regulates
⊣
HNRNPK12052863SIGNOR-88907
MAPK8phosphorylation
up-regulates
→
HNRNPK
PSer353
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-105251
ERK1/2phosphorylation
up-regulates
→
HNRNPK
PSer353
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-105754
SRCphosphorylation
up-regulates
→
HNRNPK
PTyr72
phosphorylation
down-regulates
⊣
HNRNPK12052863SIGNOR-88919
MAPK3phosphorylation
up-regulates
→
HNRNPK
PSer284
phosphorylation
down-regulates
⊣
HNRNPK11231586SIGNOR-105238
MAPK8phosphorylation
up-regulates
→
HNRNPK
PSer353
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-105770
MAPK10phosphorylation
up-regulates
→
HNRNPK
PSer353
phosphorylation
up-regulates
→
HNRNPK11259409SIGNOR-250083
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCDphosphorylation
→
unknown
HNRNPKSIGNOR-260877
JNKphosphorylation
→
up-regulates
HNRNPKSIGNOR-105758
MAPK8phosphorylation
→
up-regulates
HNRNPKSIGNOR-105766
SRCphosphorylation
img/direct_inhibition.png
down-regulates
HNRNPKSIGNOR-88911
SRCphosphorylation
img/direct_inhibition.png
down-regulates
HNRNPKSIGNOR-88899
SRCphosphorylation
img/direct_inhibition.png
down-regulates
HNRNPKSIGNOR-88915
SRCphosphorylation
img/direct_inhibition.png
down-regulates
HNRNPKSIGNOR-88903
MAPK8phosphorylation
→
up-regulates activity
HNRNPKSIGNOR-105247
MAPK10phosphorylation
→
down-regulates activity
HNRNPKSIGNOR-250082
JNKphosphorylation
→
up-regulates
HNRNPKSIGNOR-105762
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates
HNRNPKSIGNOR-145375
MAPK10phosphorylation
→
up-regulates activity
HNRNPKSIGNOR-250081
PRKCDphosphorylation
img/direct_inhibition.png
down-regulates
HNRNPKSIGNOR-67515
SRCphosphorylation
img/direct_inhibition.png
down-regulates
HNRNPKSIGNOR-88907
MAPK8phosphorylation
→
up-regulates activity
HNRNPKSIGNOR-105251
ERK1/2phosphorylation
→
up-regulates
HNRNPKSIGNOR-105754
SRCphosphorylation
img/direct_inhibition.png
down-regulates
HNRNPKSIGNOR-88919
MAPK3phosphorylation
→
down-regulates activity
HNRNPKSIGNOR-105238
MAPK8phosphorylation
→
up-regulates
HNRNPKSIGNOR-105770
MAPK10phosphorylation
→
up-regulates activity
HNRNPKSIGNOR-250083