| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | YWHAZ | Ser184 | FYYEILNsPEKACSL | phosphorylation down-regulates | 15071501 | SIGNOR-124020 |
| MAPK9 | YWHAZ | Ser184 | FYYEILNsPEKACSL | phosphorylation down-regulates | 15071501 | SIGNOR-124031 |
| MAPK10 | YWHAZ | Ser184 | FYYEILNsPEKACSL | phosphorylation down-regulates | 15071501 | SIGNOR-124009 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | phosphorylation up-regulates → | YWHAZ PSer184 | phosphorylation down-regulates ⊣ | YWHAZ | 15071501 | SIGNOR-124020 |
| MAPK9 | phosphorylation up-regulates → | YWHAZ PSer184 | phosphorylation down-regulates ⊣ | YWHAZ | 15071501 | SIGNOR-124031 |
| MAPK10 | phosphorylation up-regulates → | YWHAZ PSer184 | phosphorylation down-regulates ⊣ | YWHAZ | 15071501 | SIGNOR-124009 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK8 | phosphorylation down-regulates | YWHAZ | SIGNOR-124020 |
| MAPK9 | phosphorylation down-regulates | YWHAZ | SIGNOR-124031 |
| MAPK10 | phosphorylation down-regulates | YWHAZ | SIGNOR-124009 |
