| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN6 | ACTG1 | Tyr218 | DIKEKLCyVALDFEQ | dephosphorylation down-regulates | 12646642 | SIGNOR-99565 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN6 | dephosphorylation down-regulates ⊣ | ACTG1 PTyr218 | dephosphorylation up-regulates → | ACTG1 | 12646642 | SIGNOR-99565 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN6 | dephosphorylation![]() down-regulates | ACTG1 | SIGNOR-99565 |