| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2B | EIF5 | Ser174 | DKENGSVsSSETPPP | phosphorylation up-regulates activity | 11861906 | SIGNOR-251068 |
| CSNK2B | FGF14 | Ser228 | PGVTPSKsTSASAIM | phosphorylation up-regulates activity | 26917740 | SIGNOR-275744 |
| CSNK2B | IRS1 | Thr88 | KHLVALYtRDEHFAI | phosphorylation unknown | 8349691 | SIGNOR-251076 |
| CSNK2B | CD163 | Ser1085 | RQRLAVSsRGENLVH | phosphorylation up-regulates activity | 11298324 | SIGNOR-251056 |
| CSNK2B | CTNNB1 | Ser29 | VSHWQQQsYLDSGIH | phosphorylation up-regulates activity | 12432063 | SIGNOR-251065 |
| CSNK2B | IRS1 | Thr502 | TPGTGLGtSPALAGD | phosphorylation unknown | 8349691 | SIGNOR-251077 |
| CSNK2B | BRCA1 | Ser1572 | ESGISLFsDDPESDP | phosphorylation unknown | 10403822 | SIGNOR-251055 |
| CSNK2B | SEC63 | Ser576 | VSDKGSDsEEEETNR | phosphorylation up-regulates activity | 23287549 | SIGNOR-265268 |
| CSNK2B | FGF14 | Ser230 | VTPSKSTsASAIMNG | phosphorylation up-regulates activity | 26917740 | SIGNOR-275745 |
| CSNK2B | CDC34 | Ser203 | APAPDEGsDLFYDDY | phosphorylation unknown | 11546811 | SIGNOR-251057 |
| CSNK2B | SEC63 | Ser574 | EEVSDKGsDSEEEET | phosphorylation up-regulates activity | 23287549 | SIGNOR-265270 |
| CSNK2B | SEC63 | Ser748 | DSEGFEDsFEEEEEE | phosphorylation up-regulates activity | 23287549 | SIGNOR-265272 |
| CSNK2B | SORT1 | Ser825 | KSGYHDDsDEDLLE | phosphorylation up-regulates quantity by stabilization | 25805502 | SIGNOR-273636 |
| CSNK2B | IKZF1 | Ser13 | GQDMSQVsGKESPPV | phosphorylation down-regulates | 21750978 | SIGNOR-174844 |
| CSNK2B | BID | Thr59 | EGYDELQtDGNRSSH | phosphorylation up-regulates activity | 11583622 | SIGNOR-251054 |
| CSNK2B | CDC34 | Ser222 | EVEEEADsCFGDDED | phosphorylation unknown | 11546811 | SIGNOR-251058 |
| CSNK2B | CDC34 | Ser236 | DDSGTEEs | phosphorylation unknown | 12037680 | SIGNOR-251060 |
| CSNK2B | MME | Ser6 | sQMDITDI | phosphorylation unknown | 8943850 | SIGNOR-251078 |
| CSNK2B | IRS1 | Ser99 | HFAIAADsEAEQDSW | phosphorylation unknown | 8349691 | SIGNOR-251074 |
| CSNK2B | OCLN | Ser408 | DYTTGGEsCDELEED | phosphorylation unknown | 12804768 | SIGNOR-251079 |
| CSNK2B | SCN2A | Ser1126 | TEEFSSEsDMEESKE | phosphorylation up-regulates activity | 19064667 | SIGNOR-275760 |
| CSNK2B | OCLN | Thr404 | HYETDYTtGGESCDE | phosphorylation unknown | 12804768 | SIGNOR-251080 |
| CSNK2B | CTNNB1 | Thr112 | EGMQIPStQFDAAHP | phosphorylation up-regulates activity | 12432063 | SIGNOR-251067 |
| CSNK2B | IRS1 | Thr811 | ADDSSSStSSDSLGG | phosphorylation unknown | 8349691 | SIGNOR-251075 |
| CSNK2B | IKZF1 | Ser101 | GSHRDQGsSALSGVG | phosphorylation down-regulates | 21750978 | SIGNOR-174840 |
| CSNK2B | CTNNB1 | Thr102 | RAAMFPEtLDEGMQI | phosphorylation up-regulates activity | 12432063 | SIGNOR-251066 |
| CSNK2B | IKZF1 | Thr23 | ESPPVSDtPDEGDEP | phosphorylation down-regulates | 21750978 | SIGNOR-174856 |
| CSNK2B | HOXB6 | Ser214 | LLSASQLsAEEEEEK | phosphorylation unknown | 10327653 | SIGNOR-251071 |
| CSNK2B | EIF5 | Ser389 | LKEAEEEsSGGEEED | phosphorylation up-regulates activity | 11861906 | SIGNOR-251069 |
| CSNK2B | IKZF1 | Ser295 | LSDTPYDsSASYEKE | phosphorylation down-regulates | 21750978 | SIGNOR-174848 |
| CSNK2B | SCN2A | Ser1124 | LNTEEFSsESDMEES | phosphorylation up-regulates activity | 19064667 | SIGNOR-275756 |
| CSNK2B | IKZF1 | Ser63 | NVKVETQsDEENGRA | phosphorylation down-regulates | 21750978 | SIGNOR-174852 |
| CSNK2B | CSNK2B | Ser2 | sSSEEVSW | phosphorylation unknown | 1939094 | SIGNOR-251062 |
| CSNK2B | RNF7 | Thr10 | DVEDGEEtCALASHS | phosphorylation up-regulates activity | 12748192 | SIGNOR-251081 |
| CSNK2B | IRS1 | Ser24 | GYLRKPKsMHKRFFV | phosphorylation unknown | 8349691 | SIGNOR-251072 |
| CSNK2B | CACNA1S | Ser1575 | PEICRTVsGDLAAEE | phosphorylation up-regulates activity | 20937870 | SIGNOR-263115 |
| CSNK2B | IRS1 | Ser330 | SFRVRASsDGEGTMS | phosphorylation unknown | 8349691 | SIGNOR-251073 |
| CSNK2B | ATF4 | Ser215 | IKEEDTPsDNDSGIC | phosphorylation down-regulates quantity by destabilization | 23123191 | SIGNOR-276424 |
| CSNK2B | CTDP1 | Ser740 | TKAQRENsPAAFPDR | phosphorylation down-regulates activity | 12591939 | SIGNOR-251064 |
| CSNK2B | BID | Ser64 | LQTDGNRsSHSRLGR | phosphorylation up-regulates activity | 11583622 | SIGNOR-251053 |
| CSNK2B | SCN2A | Ser1112 | VPIAVGEsDFENLNT | phosphorylation up-regulates activity | 19064667 | SIGNOR-275752 |
| CSNK2B | EIF5 | Ser390 | KEAEEESsGGEEEDE | phosphorylation up-regulates activity | 11861906 | SIGNOR-251070 |
| CSNK2B | CTDP1 | Ser575 | AGESLDQsMEEEEEE | phosphorylation down-regulates activity | 12591939 | SIGNOR-251063 |
| CSNK2B | SET | Ser9 | SAPAAKVsKKELNSN | phosphorylation down-regulates | 23374587 | SIGNOR-200806 |
| CSNK2B | CDC34 | Ser231 | FGDDEDDsGTEES | phosphorylation unknown | 11546811 | SIGNOR-251059 |
| CSNK2B | USO1 | Ser942 | EEEDELEsGDQEDED | phosphorylation up-regulates activity | 10931861 | SIGNOR-251082 |
| CSNK2B | CDC34 | Thr233 | DDEDDSGtEES | phosphorylation unknown | 11546811 | SIGNOR-251061 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2B | phosphorylation up-regulates → | EIF5 PSer174 | phosphorylation up-regulates → | EIF5 | 11861906 | SIGNOR-251068 |
| CSNK2B | phosphorylation up-regulates → | FGF14 PSer228 | phosphorylation up-regulates → | FGF14 | 26917740 | SIGNOR-275744 |
| CSNK2B | phosphorylation up-regulates → | IRS1 PThr88 | phosphorylation down-regulates ⊣ | IRS1 | 8349691 | SIGNOR-251076 |
| CSNK2B | phosphorylation up-regulates → | CD163 PSer1085 | phosphorylation up-regulates → | CD163 | 11298324 | SIGNOR-251056 |
| CSNK2B | phosphorylation up-regulates → | CTNNB1 PSer29 | phosphorylation up-regulates → | CTNNB1 | 12432063 | SIGNOR-251065 |
| CSNK2B | phosphorylation up-regulates → | IRS1 PThr502 | phosphorylation down-regulates ⊣ | IRS1 | 8349691 | SIGNOR-251077 |
| CSNK2B | phosphorylation up-regulates → | BRCA1 PSer1572 | phosphorylation down-regulates ⊣ | BRCA1 | 10403822 | SIGNOR-251055 |
| CSNK2B | phosphorylation up-regulates → | SEC63 PSer576 | phosphorylation up-regulates → | SEC63 | 23287549 | SIGNOR-265268 |
| CSNK2B | phosphorylation up-regulates → | FGF14 PSer230 | phosphorylation up-regulates → | FGF14 | 26917740 | SIGNOR-275745 |
| CSNK2B | phosphorylation up-regulates → | CDC34 PSer203 | phosphorylation down-regulates ⊣ | CDC34 | 11546811 | SIGNOR-251057 |
| CSNK2B | phosphorylation up-regulates → | SEC63 PSer574 | phosphorylation up-regulates → | SEC63 | 23287549 | SIGNOR-265270 |
| CSNK2B | phosphorylation up-regulates → | SEC63 PSer748 | phosphorylation up-regulates → | SEC63 | 23287549 | SIGNOR-265272 |
| CSNK2B | phosphorylation up-regulates → | SORT1 PSer825 | phosphorylation up-regulates → | SORT1 | 25805502 | SIGNOR-273636 |
| CSNK2B | phosphorylation up-regulates → | IKZF1 PSer13 | phosphorylation down-regulates ⊣ | IKZF1 | 21750978 | SIGNOR-174844 |
| CSNK2B | phosphorylation up-regulates → | BID PThr59 | phosphorylation up-regulates → | BID | 11583622 | SIGNOR-251054 |
| CSNK2B | phosphorylation up-regulates → | CDC34 PSer222 | phosphorylation down-regulates ⊣ | CDC34 | 11546811 | SIGNOR-251058 |
| CSNK2B | phosphorylation up-regulates → | CDC34 PSer236 | phosphorylation down-regulates ⊣ | CDC34 | 12037680 | SIGNOR-251060 |
| CSNK2B | phosphorylation up-regulates → | MME PSer6 | phosphorylation down-regulates ⊣ | MME | 8943850 | SIGNOR-251078 |
| CSNK2B | phosphorylation up-regulates → | IRS1 PSer99 | phosphorylation down-regulates ⊣ | IRS1 | 8349691 | SIGNOR-251074 |
| CSNK2B | phosphorylation up-regulates → | OCLN PSer408 | phosphorylation down-regulates ⊣ | OCLN | 12804768 | SIGNOR-251079 |
| CSNK2B | phosphorylation up-regulates → | SCN2A PSer1126 | phosphorylation up-regulates → | SCN2A | 19064667 | SIGNOR-275760 |
| CSNK2B | phosphorylation up-regulates → | OCLN PThr404 | phosphorylation down-regulates ⊣ | OCLN | 12804768 | SIGNOR-251080 |
| CSNK2B | phosphorylation up-regulates → | CTNNB1 PThr112 | phosphorylation up-regulates → | CTNNB1 | 12432063 | SIGNOR-251067 |
| CSNK2B | phosphorylation up-regulates → | IRS1 PThr811 | phosphorylation down-regulates ⊣ | IRS1 | 8349691 | SIGNOR-251075 |
| CSNK2B | phosphorylation up-regulates → | IKZF1 PSer101 | phosphorylation down-regulates ⊣ | IKZF1 | 21750978 | SIGNOR-174840 |
| CSNK2B | phosphorylation up-regulates → | CTNNB1 PThr102 | phosphorylation up-regulates → | CTNNB1 | 12432063 | SIGNOR-251066 |
| CSNK2B | phosphorylation up-regulates → | IKZF1 PThr23 | phosphorylation down-regulates ⊣ | IKZF1 | 21750978 | SIGNOR-174856 |
| CSNK2B | phosphorylation up-regulates → | HOXB6 PSer214 | phosphorylation down-regulates ⊣ | HOXB6 | 10327653 | SIGNOR-251071 |
| CSNK2B | phosphorylation up-regulates → | EIF5 PSer389 | phosphorylation up-regulates → | EIF5 | 11861906 | SIGNOR-251069 |
| CSNK2B | phosphorylation up-regulates → | IKZF1 PSer295 | phosphorylation down-regulates ⊣ | IKZF1 | 21750978 | SIGNOR-174848 |
| CSNK2B | phosphorylation up-regulates → | SCN2A PSer1124 | phosphorylation up-regulates → | SCN2A | 19064667 | SIGNOR-275756 |
| CSNK2B | phosphorylation up-regulates → | IKZF1 PSer63 | phosphorylation down-regulates ⊣ | IKZF1 | 21750978 | SIGNOR-174852 |
| CSNK2B | phosphorylation up-regulates → | CSNK2B PSer2 | phosphorylation down-regulates ⊣ | CSNK2B | 1939094 | SIGNOR-251062 |
| CSNK2B | phosphorylation up-regulates → | RNF7 PThr10 | phosphorylation up-regulates → | RNF7 | 12748192 | SIGNOR-251081 |
| CSNK2B | phosphorylation up-regulates → | IRS1 PSer24 | phosphorylation down-regulates ⊣ | IRS1 | 8349691 | SIGNOR-251072 |
| CSNK2B | phosphorylation up-regulates → | CACNA1S PSer1575 | phosphorylation up-regulates → | CACNA1S | 20937870 | SIGNOR-263115 |
| CSNK2B | phosphorylation up-regulates → | IRS1 PSer330 | phosphorylation down-regulates ⊣ | IRS1 | 8349691 | SIGNOR-251073 |
| CSNK2B | phosphorylation up-regulates → | ATF4 PSer215 | phosphorylation down-regulates ⊣ | ATF4 | 23123191 | SIGNOR-276424 |
| CSNK2B | phosphorylation up-regulates → | CTDP1 PSer740 | phosphorylation down-regulates ⊣ | CTDP1 | 12591939 | SIGNOR-251064 |
| CSNK2B | phosphorylation up-regulates → | BID PSer64 | phosphorylation up-regulates → | BID | 11583622 | SIGNOR-251053 |
| CSNK2B | phosphorylation up-regulates → | SCN2A PSer1112 | phosphorylation up-regulates → | SCN2A | 19064667 | SIGNOR-275752 |
| CSNK2B | phosphorylation up-regulates → | EIF5 PSer390 | phosphorylation up-regulates → | EIF5 | 11861906 | SIGNOR-251070 |
| CSNK2B | phosphorylation up-regulates → | CTDP1 PSer575 | phosphorylation down-regulates ⊣ | CTDP1 | 12591939 | SIGNOR-251063 |
| CSNK2B | phosphorylation up-regulates → | SET PSer9 | phosphorylation down-regulates ⊣ | SET | 23374587 | SIGNOR-200806 |
| CSNK2B | phosphorylation up-regulates → | CDC34 PSer231 | phosphorylation down-regulates ⊣ | CDC34 | 11546811 | SIGNOR-251059 |
| CSNK2B | phosphorylation up-regulates → | USO1 PSer942 | phosphorylation up-regulates → | USO1 | 10931861 | SIGNOR-251082 |
| CSNK2B | phosphorylation up-regulates → | CDC34 PThr233 | phosphorylation down-regulates ⊣ | CDC34 | 11546811 | SIGNOR-251061 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2B | phosphorylation → up-regulates activity | EIF5 | SIGNOR-251068 |
| CSNK2B | phosphorylation → up-regulates activity | FGF14 | SIGNOR-275744 |
| CSNK2B | phosphorylation → unknown | IRS1 | SIGNOR-251076 |
| CSNK2B | phosphorylation → up-regulates activity | CD163 | SIGNOR-251056 |
| CSNK2B | phosphorylation → up-regulates activity | CTNNB1 | SIGNOR-251065 |
| CSNK2B | phosphorylation → unknown | IRS1 | SIGNOR-251077 |
| CSNK2B | phosphorylation → unknown | BRCA1 | SIGNOR-251055 |
| CSNK2B | phosphorylation → up-regulates activity | SEC63 | SIGNOR-265268 |
| CSNK2B | phosphorylation → up-regulates activity | FGF14 | SIGNOR-275745 |
| CSNK2B | phosphorylation → unknown | CDC34 | SIGNOR-251057 |
| CSNK2B | phosphorylation → up-regulates activity | SEC63 | SIGNOR-265270 |
| CSNK2B | phosphorylation → up-regulates activity | SEC63 | SIGNOR-265272 |
| CSNK2B | phosphorylation → up-regulates quantity by stabilization | SORT1 | SIGNOR-273636 |
| CSNK2B | phosphorylation down-regulates | IKZF1 | SIGNOR-174844 |
| CSNK2B | phosphorylation → up-regulates activity | BID | SIGNOR-251054 |
| CSNK2B | phosphorylation → unknown | CDC34 | SIGNOR-251058 |
| CSNK2B | phosphorylation → unknown | CDC34 | SIGNOR-251060 |
| CSNK2B | phosphorylation → unknown | MME | SIGNOR-251078 |
| CSNK2B | phosphorylation → unknown | IRS1 | SIGNOR-251074 |
| CSNK2B | phosphorylation → unknown | OCLN | SIGNOR-251079 |
| CSNK2B | phosphorylation → up-regulates activity | SCN2A | SIGNOR-275760 |
| CSNK2B | phosphorylation → unknown | OCLN | SIGNOR-251080 |
| CSNK2B | phosphorylation → up-regulates activity | CTNNB1 | SIGNOR-251067 |
| CSNK2B | phosphorylation → unknown | IRS1 | SIGNOR-251075 |
| CSNK2B | phosphorylation down-regulates | IKZF1 | SIGNOR-174840 |
| CSNK2B | phosphorylation → up-regulates activity | CTNNB1 | SIGNOR-251066 |
| CSNK2B | phosphorylation down-regulates | IKZF1 | SIGNOR-174856 |
| CSNK2B | phosphorylation → unknown | HOXB6 | SIGNOR-251071 |
| CSNK2B | phosphorylation → up-regulates activity | EIF5 | SIGNOR-251069 |
| CSNK2B | phosphorylation down-regulates | IKZF1 | SIGNOR-174848 |
| CSNK2B | phosphorylation → up-regulates activity | SCN2A | SIGNOR-275756 |
| CSNK2B | phosphorylation down-regulates | IKZF1 | SIGNOR-174852 |
| CSNK2B | phosphorylation → unknown | CSNK2B | SIGNOR-251062 |
| CSNK2B | phosphorylation → up-regulates activity | RNF7 | SIGNOR-251081 |
| CSNK2B | phosphorylation → unknown | IRS1 | SIGNOR-251072 |
| CSNK2B | phosphorylation → up-regulates activity | CACNA1S | SIGNOR-263115 |
| CSNK2B | phosphorylation → unknown | IRS1 | SIGNOR-251073 |
| CSNK2B | phosphorylation down-regulates quantity by destabilization | ATF4 | SIGNOR-276424 |
| CSNK2B | phosphorylation → down-regulates activity | CTDP1 | SIGNOR-251064 |
| CSNK2B | phosphorylation → up-regulates activity | BID | SIGNOR-251053 |
| CSNK2B | phosphorylation → up-regulates activity | SCN2A | SIGNOR-275752 |
| CSNK2B | phosphorylation → up-regulates activity | EIF5 | SIGNOR-251070 |
| CSNK2B | phosphorylation → down-regulates activity | CTDP1 | SIGNOR-251063 |
| CSNK2B | phosphorylation down-regulates | SET | SIGNOR-200806 |
| CSNK2B | phosphorylation → unknown | CDC34 | SIGNOR-251059 |
| CSNK2B | phosphorylation → up-regulates activity | USO1 | SIGNOR-251082 |
| CSNK2B | phosphorylation → unknown | CDC34 | SIGNOR-251061 |
