| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PASK | EEF1A1 | – | phosphorylation unknown | 17595531 | SIGNOR-245862 | |
| PRKCB | EEF1A1 | Ser53 | AAEMGKGsFKYAWVL | phosphorylation up-regulates activity | 20923971 | SIGNOR-263167 |
| PRKCD | EEF1A1 | Thr432 | AVRDMRQtVAVGVIK | phosphorylation unknown | 7890750 | SIGNOR-248902 |
| BRAF | EEF1A1 | Thr88 | ETSKYYVtIIDAPGH | phosphorylation down-regulates quantity by destabilization | 22378069 | SIGNOR-276405 |
| BRAF | EEF1A1 | Ser21 | GHVDSGKsTTTGHLI | phosphorylation down-regulates quantity by destabilization | 22378069 | SIGNOR-276404 |
| TGFBR1 | EEF1A1 | Ser300 | EMHHEALsEALPGDN | phosphorylation down-regulates | 20832312 | SIGNOR-167943 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | phosphorylation up-regulates → | EEF1A1 PSer53 | phosphorylation up-regulates → | EEF1A1 | 20923971 | SIGNOR-263167 |
| PRKCD | phosphorylation up-regulates → | EEF1A1 PThr432 | phosphorylation down-regulates ⊣ | EEF1A1 | 7890750 | SIGNOR-248902 |
| BRAF | phosphorylation up-regulates → | EEF1A1 PThr88 | phosphorylation down-regulates ⊣ | EEF1A1 | 22378069 | SIGNOR-276405 |
| BRAF | phosphorylation up-regulates → | EEF1A1 PSer21 | phosphorylation down-regulates ⊣ | EEF1A1 | 22378069 | SIGNOR-276404 |
| TGFBR1 | phosphorylation up-regulates → | EEF1A1 PSer300 | phosphorylation down-regulates ⊣ | EEF1A1 | 20832312 | SIGNOR-167943 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PASK | phosphorylation → unknown | EEF1A1 | SIGNOR-245862 |
| PRKCB | phosphorylation → up-regulates activity | EEF1A1 | SIGNOR-263167 |
| PRKCD | phosphorylation → unknown | EEF1A1 | SIGNOR-248902 |
| BRAF | phosphorylation![]() down-regulates quantity by destabilization | EEF1A1 | SIGNOR-276405 |
| BRAF | phosphorylation![]() down-regulates quantity by destabilization | EEF1A1 | SIGNOR-276404 |
| TGFBR1 | phosphorylation![]() down-regulates | EEF1A1 | SIGNOR-167943 |