Entity Details

Name BTK_Tyr248
ID P78347
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCGTF2ITyr248EESEDPDyYQYNIQAphosphorylation
up-regulates activity		11934902SIGNOR-247185
JAK2GTF2ITyr248EESEDPDyYQYNIQAphosphorylation
up-regulates activity		11313464SIGNOR-235313
BTKGTF2ITyr248EESEDPDyYQYNIQAphosphorylation
up-regulates activity		11373296SIGNOR-108338
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
GTF2I
PTyr248		phosphorylation
up-regulates
→		GTF2I11934902SIGNOR-247185
JAK2phosphorylation
up-regulates
→
GTF2I
PTyr248		phosphorylation
up-regulates
→		GTF2I11313464SIGNOR-235313
BTKphosphorylation
up-regulates
→
GTF2I
PTyr248		phosphorylation
up-regulates
→		GTF2I11373296SIGNOR-108338
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		GTF2ISIGNOR-247185
JAK2phosphorylation
→
up-regulates activity 		GTF2ISIGNOR-235313
BTKphosphorylation
→
up-regulates activity 		GTF2ISIGNOR-108338