| Name | SRPK2 |
| ID | P78362 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 81-684 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KB1 | SRPK2 | Ser494 | HDRSRTVsASSTGDL | phosphorylation up-regulates activity | 29153836 | SIGNOR-275459 |
| AKT1 | SRPK2 | Thr492 | PSHDRSRtVSASSTG | phosphorylation up-regulates | 19592491 | SIGNOR-186760 |
| AKT | SRPK2 | Thr492 | PSHDRSRtVSASSTG | phosphorylation up-regulates | 19592491 | SIGNOR-244341 |
| CSNK1A1 | SRPK2 | Ser497 | SRTVSASsTGDLPKA | phosphorylation up-regulates activity | 29153836 | SIGNOR-275460 |
| RPS6KB1 | SRPK2 | – | phosphorylation up-regulates activity | 35674408 | SIGNOR-280121 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KB1 | phosphorylation up-regulates → | SRPK2 PSer494 | phosphorylation up-regulates → | SRPK2 | 29153836 | SIGNOR-275459 |
| AKT1 | phosphorylation up-regulates → | SRPK2 PThr492 | phosphorylation up-regulates → | SRPK2 | 19592491 | SIGNOR-186760 |
| AKT | phosphorylation up-regulates → | SRPK2 PThr492 | phosphorylation up-regulates → | SRPK2 | 19592491 | SIGNOR-244341 |
| CSNK1A1 | phosphorylation up-regulates → | SRPK2 PSer497 | phosphorylation up-regulates → | SRPK2 | 29153836 | SIGNOR-275460 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KB1 | phosphorylation → up-regulates activity | SRPK2 | SIGNOR-275459 |
| AKT1 | phosphorylation → up-regulates | SRPK2 | SIGNOR-186760 |
| AKT | phosphorylation → up-regulates | SRPK2 | SIGNOR-244341 |
| CSNK1A1 | phosphorylation → up-regulates activity | SRPK2 | SIGNOR-275460 |
| RPS6KB1 | phosphorylation → up-regulates activity | SRPK2 | SIGNOR-280121 |