Entity Details

Name CSNK1G2
ID P78368
Role kinase
Enzymatic Domains
Protein kinase 46-316
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSNK1G2IRS4Ser859KDAASKPsGEGSFSKphosphorylation
down-regulates quantity by destabilization
30026872SIGNOR-277615
CSNK1G2PER1phosphorylation
down-regulates
15917222SIGNOR-137751
CSNK1G2LYNSer13SKGKDSLsDDGVDLKphosphorylation
up-regulates quantity by stabilization
33004926SIGNOR-275397
CSNK1G2SMAD3Ser418LTQMGSPsIRCSSVSphosphorylation
down-regulates
18794808SIGNOR-181069
CSNK1G2MTA1phosphorylation
up-regulates activity
15077195SIGNOR-280236
CSNK1G2CERT1Ser132SSLRRHGsMVSLVSGphosphorylation
down-regulates
19005213SIGNOR-182160
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK1G2phosphorylation
up-regulates
IRS4
PSer859
phosphorylation
down-regulates
IRS430026872SIGNOR-277615
CSNK1G2phosphorylation
up-regulates
LYN
PSer13
phosphorylation
up-regulates
LYN33004926SIGNOR-275397
CSNK1G2phosphorylation
up-regulates
SMAD3
PSer418
phosphorylation
down-regulates
SMAD318794808SIGNOR-181069
CSNK1G2phosphorylation
up-regulates
CERT1
PSer132
phosphorylation
down-regulates
CERT119005213SIGNOR-182160
Regulator Mechanism/Effect Target SIGNOR-ID
CSNK1G2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
IRS4SIGNOR-277615
CSNK1G2phosphorylation
img/direct_inhibition.png
down-regulates
PER1SIGNOR-137751
CSNK1G2phosphorylation

up-regulates quantity by stabilization
LYNSIGNOR-275397
CSNK1G2phosphorylation
img/direct_inhibition.png
down-regulates
SMAD3SIGNOR-181069
CSNK1G2phosphorylation

up-regulates activity
MTA1SIGNOR-280236
CSNK1G2phosphorylation
img/direct_inhibition.png
down-regulates
CERT1SIGNOR-182160