| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA1 | CCT2 | Ser260 | GSRVRVDsTAKVAEI | phosphorylation up-regulates | 21440620 | SIGNOR-172986 |
| RPS6K | CCT2 | Ser260 | GSRVRVDsTAKVAEI | phosphorylation up-regulates | 21440620 | SIGNOR-252780 |
| RPS6KB1 | CCT2 | Ser260 | GSRVRVDsTAKVAEI | phosphorylation unknown | 19332537 | SIGNOR-184926 |
| AKT1 | CCT2 | Ser260 | GSRVRVDsTAKVAEI | phosphorylation unknown | 19332537 | SIGNOR-184922 |
| AKT | CCT2 | Ser260 | GSRVRVDsTAKVAEI | phosphorylation unknown | 19332537 | SIGNOR-244172 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA1 | phosphorylation up-regulates → | CCT2 PSer260 | phosphorylation up-regulates → | CCT2 | 21440620 | SIGNOR-172986 |
| RPS6K | phosphorylation up-regulates → | CCT2 PSer260 | phosphorylation up-regulates → | CCT2 | 21440620 | SIGNOR-252780 |
| RPS6KB1 | phosphorylation up-regulates → | CCT2 PSer260 | phosphorylation down-regulates ⊣ | CCT2 | 19332537 | SIGNOR-184926 |
| AKT1 | phosphorylation up-regulates → | CCT2 PSer260 | phosphorylation down-regulates ⊣ | CCT2 | 19332537 | SIGNOR-184922 |
| AKT | phosphorylation up-regulates → | CCT2 PSer260 | phosphorylation down-regulates ⊣ | CCT2 | 19332537 | SIGNOR-244172 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KA1 | phosphorylation → up-regulates | CCT2 | SIGNOR-172986 |
| RPS6K | phosphorylation → up-regulates | CCT2 | SIGNOR-252780 |
| RPS6KB1 | phosphorylation → unknown | CCT2 | SIGNOR-184926 |
| AKT1 | phosphorylation → unknown | CCT2 | SIGNOR-184922 |
| AKT | phosphorylation → unknown | CCT2 | SIGNOR-244172 |
