Entity Details

Name ADARB1
ID P78563
Role substrate
Enzymatic Domains
DRBM 1 78-144
PROSITE-ProRule
DRBM 2 231-298
PROSITE-ProRule
A to I editase 370-737
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCZADARB1Ser211GDLSLSAsPVPASLAphosphorylation
up-regulates activity		29694894SIGNOR-277392
PRKCZADARB1Ser216SASPVPAsLAQPPLPphosphorylation
up-regulates activity		29694894SIGNOR-277391
AKT2ADARB1Thr553LQGERLLtMSCSDKIphosphorylation
down-regulates activity		31095429SIGNOR-276196
AKTADARB1Thr553LQGERLLtMSCSDKIphosphorylation
down-regulates activity		31095429SIGNOR-266358
AKT1ADARB1Thr553LQGERLLtMSCSDKIphosphorylation
down-regulates activity		31095429SIGNOR-276194
AKT3ADARB1Thr553LQGERLLtMSCSDKIphosphorylation
down-regulates activity		31095429SIGNOR-276195
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCZphosphorylation
up-regulates
→
ADARB1
PSer211		phosphorylation
up-regulates
→		ADARB129694894SIGNOR-277392
PRKCZphosphorylation
up-regulates
→
ADARB1
PSer216		phosphorylation
up-regulates
→		ADARB129694894SIGNOR-277391
AKT2phosphorylation
up-regulates
→
ADARB1
PThr553		phosphorylation
down-regulates
⊣		ADARB131095429SIGNOR-276196
AKTphosphorylation
up-regulates
→
ADARB1
PThr553		phosphorylation
down-regulates
⊣		ADARB131095429SIGNOR-266358
AKT1phosphorylation
up-regulates
→
ADARB1
PThr553		phosphorylation
down-regulates
⊣		ADARB131095429SIGNOR-276194
AKT3phosphorylation
up-regulates
→
ADARB1
PThr553		phosphorylation
down-regulates
⊣		ADARB131095429SIGNOR-276195
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCZphosphorylation
→
up-regulates activity 		ADARB1SIGNOR-277392
PRKCZphosphorylation
→
up-regulates activity 		ADARB1SIGNOR-277391
AKT2phosphorylation
→
down-regulates activity 		ADARB1SIGNOR-276196
AKTphosphorylation
→
down-regulates activity 		ADARB1SIGNOR-266358
AKT1phosphorylation
→
down-regulates activity 		ADARB1SIGNOR-276194
AKT3phosphorylation
→
down-regulates activity 		ADARB1SIGNOR-276195