Entity Details

Name CDK5
ID Q00535
Role substrate
Enzymatic Domains
Protein kinase 4-286
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSNK1A1CDK5Ser159GIPVRCYsAEVVTLWphosphorylation
up-regulates activity		10500146SIGNOR-275966
PRKCDCDK5Thr77LHSDKKLtLVFEFCDphosphorylation
down-regulates activity		29511352SIGNOR-277386
ABL1CDK5Tyr15
View in OncoXplorer
EKIGEGTyGTVFKAKphosphorylation
up-regulates activity		10896159SIGNOR-245288
FYNCDK5Tyr15
View in OncoXplorer
EKIGEGTyGTVFKAKphosphorylation
up-regulates activity		14757045SIGNOR-251156
CSNK1DCDK5Ser159GIPVRCYsAEVVTLWphosphorylation
up-regulates activity		10500146SIGNOR-250798
CDK7CDK5Ser159GIPVRCYsAEVVTLWphosphorylation
up-regulates activity		14586172SIGNOR-278923
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK1A1phosphorylation
up-regulates
→
CDK5
PSer159		phosphorylation
up-regulates
→		CDK510500146SIGNOR-275966
PRKCDphosphorylation
up-regulates
→
CDK5
PThr77		phosphorylation
down-regulates
⊣		CDK529511352SIGNOR-277386
ABL1phosphorylation
up-regulates
→
CDK5
PTyr15		phosphorylation
up-regulates
→		CDK510896159SIGNOR-245288
FYNphosphorylation
up-regulates
→
CDK5
PTyr15		phosphorylation
up-regulates
→		CDK514757045SIGNOR-251156
CSNK1Dphosphorylation
up-regulates
→
CDK5
PSer159		phosphorylation
up-regulates
→		CDK510500146SIGNOR-250798
CDK7phosphorylation
up-regulates
→
CDK5
PSer159		phosphorylation
up-regulates
→		CDK514586172SIGNOR-278923
Regulator Mechanism/Effect Target SIGNOR-ID
CSNK1A1phosphorylation
→
up-regulates activity 		CDK5SIGNOR-275966
PRKCDphosphorylation
→
down-regulates activity 		CDK5SIGNOR-277386
ABL1phosphorylation
→
up-regulates activity 		CDK5SIGNOR-245288
FYNphosphorylation
→
up-regulates activity 		CDK5SIGNOR-251156
CSNK1Dphosphorylation
→
up-regulates activity 		CDK5SIGNOR-250798
CDK7phosphorylation
→
up-regulates activity 		CDK5SIGNOR-278923