Entity Details

Name NFKB2
ID Q00653
Role substrate
Enzymatic Domains
RHD 38-343
PROSITE-ProRule
Death 764-851
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CHUKNFKB2Ser870KEDSAYGsQSVEQEAphosphorylation
up-regulates activity		15084608SIGNOR-124230
GSK3BNFKB2Ser707EPLCPLPsPPTSDSDphosphorylation
down-regulates activity		26999213SIGNOR-279186
MAP3K14NFKB2Ser870KEDSAYGsQSVEQEAphosphorylation
up-regulates activity		11239468SIGNOR-105557
GSK3BNFKB2Ser711PLPSPPTsDSDSDSEphosphorylation
down-regulates activity		26999213SIGNOR-279187
MAP3K14NFKB2Ser866TAEVKEDsAYGSQSVphosphorylation
up-regulates activity		11239468SIGNOR-105553
CHUKNFKB2Ser866TAEVKEDsAYGSQSVphosphorylation
up-regulates activity		15084608SIGNOR-124226
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CHUKphosphorylation
up-regulates
→
NFKB2
PSer870		phosphorylation
up-regulates
→		NFKB215084608SIGNOR-124230
GSK3Bphosphorylation
up-regulates
→
NFKB2
PSer707		phosphorylation
down-regulates
⊣		NFKB226999213SIGNOR-279186
MAP3K14phosphorylation
up-regulates
→
NFKB2
PSer870		phosphorylation
up-regulates
→		NFKB211239468SIGNOR-105557
GSK3Bphosphorylation
up-regulates
→
NFKB2
PSer711		phosphorylation
down-regulates
⊣		NFKB226999213SIGNOR-279187
MAP3K14phosphorylation
up-regulates
→
NFKB2
PSer866		phosphorylation
up-regulates
→		NFKB211239468SIGNOR-105553
CHUKphosphorylation
up-regulates
→
NFKB2
PSer866		phosphorylation
up-regulates
→		NFKB215084608SIGNOR-124226
Regulator Mechanism/Effect Target SIGNOR-ID
CHUKphosphorylation
→
up-regulates activity 		NFKB2SIGNOR-124230
GSK3Bphosphorylation
→
down-regulates activity 		NFKB2SIGNOR-279186
MAP3K14phosphorylation
→
up-regulates activity 		NFKB2SIGNOR-105557
GSK3Bphosphorylation
→
down-regulates activity 		NFKB2SIGNOR-279187
MAP3K14phosphorylation
→
up-regulates activity 		NFKB2SIGNOR-105553
CHUKphosphorylation
→
up-regulates activity 		NFKB2SIGNOR-124226