Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
ERK1/2	CACNA1B	Ser446	ADLCAVGsPFARASL	phosphorylation up-regulates activity	16406008	SIGNOR-262967
CAMK2A	CACNA1B	Ser2120	ERRQPSSsSSEKQRF	phosphorylation down-regulates	16982421	SIGNOR-149684

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
ERK1/2	phosphorylation up-regulates →	CACNA1B PSer446	phosphorylation up-regulates →	CACNA1B	16406008	SIGNOR-262967
CAMK2A	phosphorylation up-regulates →	CACNA1B PSer2120	phosphorylation down-regulates ⊣	CACNA1B	16982421	SIGNOR-149684

Regulator	Mechanism/Effect	Target	SIGNOR-ID
ERK1/2	phosphorylation → up-regulates activity	CACNA1B	SIGNOR-262967
CAMK2A	phosphorylation down-regulates	CACNA1B	SIGNOR-149684