Entity Details

Name CDK2_Thr273
ID Q01196
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1RUNX1Thr273SPSVHPAtPISPGRAphosphorylation
up-regulates		16046550SIGNOR-138920
CDK6RUNX1Thr273SPSVHPAtPISPGRAphosphorylation
up-regulates		16046550SIGNOR-138965
MAPK1RUNX1Thr273SPSVHPAtPISPGRAphosphorylation
down-regulates quantity by destabilization		16046550SIGNOR-268220
MAPK1RUNX1Thr273SPSVHPAtPISPGRAphosphorylation
up-regulates activity		16046550SIGNOR-138981
ERK1/2RUNX1Thr273SPSVHPAtPISPGRAphosphorylation
up-regulates		16046550SIGNOR-244715
CDK2RUNX1Thr273SPSVHPAtPISPGRAphosphorylation
up-regulates activity		16046550SIGNOR-138940
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
RUNX1
PThr273		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-138920
CDK6phosphorylation
up-regulates
→
RUNX1
PThr273		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-138965
MAPK1phosphorylation
up-regulates
→
RUNX1
PThr273		phosphorylation
down-regulates
⊣		RUNX116046550SIGNOR-268220
MAPK1phosphorylation
up-regulates
→
RUNX1
PThr273		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-138981
ERK1/2phosphorylation
up-regulates
→
RUNX1
PThr273		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-244715
CDK2phosphorylation
up-regulates
→
RUNX1
PThr273		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-138940
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
up-regulates 		RUNX1SIGNOR-138920
CDK6phosphorylation
→
up-regulates 		RUNX1SIGNOR-138965
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		RUNX1SIGNOR-268220
MAPK1phosphorylation
→
up-regulates activity 		RUNX1SIGNOR-138981
ERK1/2phosphorylation
→
up-regulates 		RUNX1SIGNOR-244715
CDK2phosphorylation
→
up-regulates activity 		RUNX1SIGNOR-138940