Entity Details

Name CyclinB/CDK1_Ser21
ID Q01196
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1RUNX1Ser21TPPSTALsPGKMSEAphosphorylation
up-regulates		21059642SIGNOR-169318
CyclinB/CDK1RUNX1Ser21TPPSTALsPGKMSEAphosphorylation
up-regulates		21059642SIGNOR-216916
CyclinD3/CDK6RUNX1Ser21TPPSTALsPGKMSEAphosphorylation
up-regulates activity		21059642SIGNOR-273031
CDK6RUNX1Ser21TPPSTALsPGKMSEAphosphorylation
up-regulates		21059642SIGNOR-169326
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
RUNX1
PSer21		phosphorylation
up-regulates
→		RUNX121059642SIGNOR-169318
CyclinB/CDK1phosphorylation
up-regulates
→
RUNX1
PSer21		phosphorylation
up-regulates
→		RUNX121059642SIGNOR-216916
CyclinD3/CDK6phosphorylation
up-regulates
→
RUNX1
PSer21		phosphorylation
up-regulates
→		RUNX121059642SIGNOR-273031
CDK6phosphorylation
up-regulates
→
RUNX1
PSer21		phosphorylation
up-regulates
→		RUNX121059642SIGNOR-169326
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
up-regulates 		RUNX1SIGNOR-169318
CyclinB/CDK1phosphorylation
→
up-regulates 		RUNX1SIGNOR-216916
CyclinD3/CDK6phosphorylation
→
up-regulates activity 		RUNX1SIGNOR-273031
CDK6phosphorylation
→
up-regulates 		RUNX1SIGNOR-169326