Entity Details

Name CyclinD3/CDK6_Ser397
ID Q01196
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK6RUNX1Ser397SMVGGERsPPRILPPphosphorylation
up-regulates		21059642SIGNOR-169330
CyclinD3/CDK6RUNX1Ser397SMVGGERsPPRILPPphosphorylation
up-regulates activity		21059642SIGNOR-273030
CDK1RUNX1Ser397SMVGGERsPPRILPPphosphorylation
up-regulates		21059642SIGNOR-169322
CyclinB/CDK1RUNX1Ser397SMVGGERsPPRILPPphosphorylation
up-regulates		21059642SIGNOR-216912
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK6phosphorylation
up-regulates
→
RUNX1
PSer397		phosphorylation
up-regulates
→		RUNX121059642SIGNOR-169330
CyclinD3/CDK6phosphorylation
up-regulates
→
RUNX1
PSer397		phosphorylation
up-regulates
→		RUNX121059642SIGNOR-273030
CDK1phosphorylation
up-regulates
→
RUNX1
PSer397		phosphorylation
up-regulates
→		RUNX121059642SIGNOR-169322
CyclinB/CDK1phosphorylation
up-regulates
→
RUNX1
PSer397		phosphorylation
up-regulates
→		RUNX121059642SIGNOR-216912
Regulator Mechanism/Effect Target SIGNOR-ID
CDK6phosphorylation
→
up-regulates 		RUNX1SIGNOR-169330
CyclinD3/CDK6phosphorylation
→
up-regulates activity 		RUNX1SIGNOR-273030
CDK1phosphorylation
→
up-regulates 		RUNX1SIGNOR-169322
CyclinB/CDK1phosphorylation
→
up-regulates 		RUNX1SIGNOR-216912