Entity Details

Name MAPK1_Ser266
ID Q01196
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK6RUNX1Ser266QYLGSIAsPSVHPATphosphorylation
up-regulates		16046550SIGNOR-138957
MAPK1RUNX1Ser266QYLGSIAsPSVHPATphosphorylation
up-regulates activity		16046550SIGNOR-138973
ERK1/2RUNX1Ser266QYLGSIAsPSVHPATphosphorylation
up-regulates		16046550SIGNOR-244707
CDK1RUNX1Ser266QYLGSIAsPSVHPATphosphorylation
up-regulates		16046550SIGNOR-138912
CDK2RUNX1Ser266QYLGSIAsPSVHPATphosphorylation
up-regulates activity		16046550SIGNOR-138932
MAPK1RUNX1Ser266QYLGSIAsPSVHPATphosphorylation
down-regulates quantity by destabilization		16046550SIGNOR-268219
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK6phosphorylation
up-regulates
→
RUNX1
PSer266		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-138957
MAPK1phosphorylation
up-regulates
→
RUNX1
PSer266		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-138973
ERK1/2phosphorylation
up-regulates
→
RUNX1
PSer266		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-244707
CDK1phosphorylation
up-regulates
→
RUNX1
PSer266		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-138912
CDK2phosphorylation
up-regulates
→
RUNX1
PSer266		phosphorylation
up-regulates
→		RUNX116046550SIGNOR-138932
MAPK1phosphorylation
up-regulates
→
RUNX1
PSer266		phosphorylation
down-regulates
⊣		RUNX116046550SIGNOR-268219
Regulator Mechanism/Effect Target SIGNOR-ID
CDK6phosphorylation
→
up-regulates 		RUNX1SIGNOR-138957
MAPK1phosphorylation
→
up-regulates activity 		RUNX1SIGNOR-138973
ERK1/2phosphorylation
→
up-regulates 		RUNX1SIGNOR-244707
CDK1phosphorylation
→
up-regulates 		RUNX1SIGNOR-138912
CDK2phosphorylation
→
up-regulates activity 		RUNX1SIGNOR-138932
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		RUNX1SIGNOR-268219