| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2B | PLCB3 | Ser537 | PSLEPQKsLGDEGLN | phosphorylation unknown | 11325525 | SIGNOR-250689 |
| MAP3K8 | PLCB3 | Ser537 | PSLEPQKsLGDEGLN | phosphorylation up-regulates activity | 21868363 | SIGNOR-278519 |
| CAMK2G | PLCB3 | Ser537 | PSLEPQKsLGDEGLN | phosphorylation unknown | 11325525 | SIGNOR-250702 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2B | phosphorylation up-regulates → | PLCB3 PSer537 | phosphorylation down-regulates ⊣ | PLCB3 | 11325525 | SIGNOR-250689 |
| MAP3K8 | phosphorylation up-regulates → | PLCB3 PSer537 | phosphorylation up-regulates → | PLCB3 | 21868363 | SIGNOR-278519 |
| CAMK2G | phosphorylation up-regulates → | PLCB3 PSer537 | phosphorylation down-regulates ⊣ | PLCB3 | 11325525 | SIGNOR-250702 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CAMK2B | phosphorylation → unknown | PLCB3 | SIGNOR-250689 |
| MAP3K8 | phosphorylation → up-regulates activity | PLCB3 | SIGNOR-278519 |
| CAMK2G | phosphorylation → unknown | PLCB3 | SIGNOR-250702 |
