| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKG2 | PLCB3 | Ser26 | VETLRRGsKFIKWDE | phosphorylation down-regulates activity | 11278298 | SIGNOR-249080 |
| PRKG1 | PLCB3 | Ser26 | VETLRRGsKFIKWDE | phosphorylation down-regulates activity | 11278298 | SIGNOR-249079 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKG2 | phosphorylation up-regulates → | PLCB3 PSer26 | phosphorylation down-regulates ⊣ | PLCB3 | 11278298 | SIGNOR-249080 |
| PRKG1 | phosphorylation up-regulates → | PLCB3 PSer26 | phosphorylation down-regulates ⊣ | PLCB3 | 11278298 | SIGNOR-249079 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKG2 | phosphorylation → down-regulates activity | PLCB3 | SIGNOR-249080 |
| PRKG1 | phosphorylation → down-regulates activity | PLCB3 | SIGNOR-249079 |