| Name | ID2 |
| ID | Q02363 |
| Role | substrate |
| Enzymatic Domains |
bHLH 23-75 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | ID2 | Ser5 | sPVRSVRK | phosphorylation down-regulates | 9029153 | SIGNOR-217320 |
| CDK2 | ID2 | Ser5 | sPVRSVRK | phosphorylation down-regulates | 9029153 | SIGNOR-46397 |
| CyclinE/CDK2 | ID2 | Ser5 | sPVRSVRK | phosphorylation down-regulates | 9029153 | SIGNOR-216698 |
| DYRK1B | ID2 | Thr27 | LGISRSKtPVDDPMS | phosphorylation down-regulates activity | 26735018 | SIGNOR-279033 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation up-regulates → | ID2 PSer5 | phosphorylation down-regulates ⊣ | ID2 | 9029153 | SIGNOR-217320 |
| CDK2 | phosphorylation up-regulates → | ID2 PSer5 | phosphorylation down-regulates ⊣ | ID2 | 9029153 | SIGNOR-46397 |
| CyclinE/CDK2 | phosphorylation up-regulates → | ID2 PSer5 | phosphorylation down-regulates ⊣ | ID2 | 9029153 | SIGNOR-216698 |
| DYRK1B | phosphorylation up-regulates → | ID2 PThr27 | phosphorylation down-regulates ⊣ | ID2 | 26735018 | SIGNOR-279033 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation down-regulates | ID2 | SIGNOR-217320 |
| CDK2 | phosphorylation down-regulates | ID2 | SIGNOR-46397 |
| CyclinE/CDK2 | phosphorylation down-regulates | ID2 | SIGNOR-216698 |
| DYRK1B | phosphorylation → down-regulates activity | ID2 | SIGNOR-279033 |