Entity Details

Name PAX5
ID Q02548
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1PAX5Ser189; Ser283SGILGITsPSADTNK;DMKANLAsPTPADIGphosphorylation
down-regulates activity		22593617SIGNOR-269087
SYKPAX5–phosphorylation
down-regulates activity		27181361SIGNOR-269084
MAPK3PAX5Ser189; Ser283SGILGITsPSADTNK;DMKANLAsPTPADIGphosphorylation
down-regulates activity		22593617SIGNOR-269086
ERK1/2PAX5Ser189; Ser283SGILGITsPSADTNK;DMKANLAsPTPADIGphosphorylation
down-regulates activity		22593617SIGNOR-269088
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
PAX5
PSer189; Ser283		phosphorylation
down-regulates
⊣		PAX522593617SIGNOR-269087
MAPK3phosphorylation
up-regulates
→
PAX5
PSer189; Ser283		phosphorylation
down-regulates
⊣		PAX522593617SIGNOR-269086
ERK1/2phosphorylation
up-regulates
→
PAX5
PSer189; Ser283		phosphorylation
down-regulates
⊣		PAX522593617SIGNOR-269088
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
down-regulates activity 		PAX5SIGNOR-269087
SYKphosphorylation
→
down-regulates activity 		PAX5SIGNOR-269084
MAPK3phosphorylation
→
down-regulates activity 		PAX5SIGNOR-269086
ERK1/2phosphorylation
→
down-regulates activity 		PAX5SIGNOR-269088