Entity Details

Name ERK1/2_Thr292
ID Q02750
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1MAP2K1Thr292ETPPRPRtPGRPLSSphosphorylation
down-regulates activity		14993270SIGNOR-236335
ERK1/2MAP2K1Thr292ETPPRPRtPGRPLSSphosphorylation
down-regulates activity		14993270SIGNOR-244557
CDK1MAP2K1Thr292ETPPRPRtPGRPLSSphosphorylation
down-regulates		8114697SIGNOR-36116
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
MAP2K1
PThr292		phosphorylation
down-regulates
⊣		MAP2K114993270SIGNOR-236335
ERK1/2phosphorylation
up-regulates
→
MAP2K1
PThr292		phosphorylation
down-regulates
⊣		MAP2K114993270SIGNOR-244557
CDK1phosphorylation
up-regulates
→
MAP2K1
PThr292		phosphorylation
down-regulates
⊣		MAP2K18114697SIGNOR-36116
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
down-regulates activity 		MAP2K1SIGNOR-236335
ERK1/2phosphorylation
→
down-regulates activity 		MAP2K1SIGNOR-244557
CDK1phosphorylation
img/direct_inhibition.png
down-regulates 		MAP2K1SIGNOR-36116