Entity Details

Name ERK1/2_Thr386
ID Q02750
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ERK1/2MAP2K1Thr386IGLNQPStPTHAAGVphosphorylation
down-regulates activity		10567369SIGNOR-244561
MAPK1MAP2K1Thr386IGLNQPStPTHAAGVphosphorylation
down-regulates activity		10567369SIGNOR-236498
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ERK1/2phosphorylation
up-regulates
→
MAP2K1
PThr386		phosphorylation
down-regulates
⊣		MAP2K110567369SIGNOR-244561
MAPK1phosphorylation
up-regulates
→
MAP2K1
PThr386		phosphorylation
down-regulates
⊣		MAP2K110567369SIGNOR-236498
Regulator Mechanism/Effect Target SIGNOR-ID
ERK1/2phosphorylation
→
down-regulates activity 		MAP2K1SIGNOR-244561
MAPK1phosphorylation
→
down-regulates activity 		MAP2K1SIGNOR-236498