Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAP3K10	TCF3	Ser341	KALASIYsPDHSSNN	phosphorylation down-regulates	19801649	SIGNOR-161523
MAP3K10	TCF3	Ser352	SSNNFSSsPSTPVGS	phosphorylation down-regulates	19801649	SIGNOR-161527
MAP3K10	TCF3	Ser359	SPSTPVGsPQGLAGT	phosphorylation down-regulates	19801649	SIGNOR-161531
MAP3K10	TCF3	Ser379	AGAPGALsPSYDGGL	phosphorylation down-regulates	19801649	SIGNOR-161540
MAP3K10	TCF3	Thr355	NFSSSPStPVGSPQG	phosphorylation down-regulates	19801649	SIGNOR-161544
MAP3K10	MAP2K4	–		phosphorylation up-regulates activity	9182538	SIGNOR-278954

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAP3K10	phosphorylation up-regulates →	TCF3 PSer341	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161523
MAP3K10	phosphorylation up-regulates →	TCF3 PSer352	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161527
MAP3K10	phosphorylation up-regulates →	TCF3 PSer359	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161531
MAP3K10	phosphorylation up-regulates →	TCF3 PSer379	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161540
MAP3K10	phosphorylation up-regulates →	TCF3 PThr355	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161544

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161523
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161527
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161531
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161540
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161544
MAP3K10	phosphorylation → up-regulates activity	MAP2K4	SIGNOR-278954