Entity Details

Name FKBP4
ID Q02790
Role substrate
Enzymatic Domains
PPIase FKBP-type 1 50-138
PROSITE-ProRule
PPIase FKBP-type 2 167-253
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN2FKBP4–dephosphorylation
down-regulates		12552015SIGNOR-97794
SRMSFKBP4–phosphorylation
down-regulates activity		34077419SIGNOR-279764
CSNK2A1FKBP4Thr143EFKGEDLtEEEDGGIphosphorylation
down-regulates activity		9405642SIGNOR-250865
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK2A1phosphorylation
up-regulates
→
FKBP4
PThr143		phosphorylation
down-regulates
⊣		FKBP49405642SIGNOR-250865
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN2dephosphorylation
img/direct_inhibition.png
down-regulates 		FKBP4SIGNOR-97794
SRMSphosphorylation
→
down-regulates activity 		FKBP4SIGNOR-279764
CSNK2A1phosphorylation
→
down-regulates activity 		FKBP4SIGNOR-250865