Entity Details

Name CREM
ID Q03060
Role substrate
Enzymatic Domains
KID 88-147
PROSITE-ProRule
bZIP 286-345
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK3CREMSer277
View in OncoXplorer
ASPGSLHsPQQLAEEphosphorylation
down-regulates quantity by destabilization		11466319SIGNOR-275978
CDK1CREMSer271
View in OncoXplorer
QGVVMAAsPGSLHSPphosphorylation
down-regulates quantity		21767532SIGNOR-276346
CDK1CREMSer277
View in OncoXplorer
ASPGSLHsPQQLAEEphosphorylation
down-regulates quantity by destabilization		11466319SIGNOR-275979
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK3phosphorylation
up-regulates
→
CREM
PSer277		phosphorylation
down-regulates
⊣		CREM11466319SIGNOR-275978
CDK1phosphorylation
up-regulates
→
CREM
PSer271		phosphorylation
down-regulates
⊣		CREM21767532SIGNOR-276346
CDK1phosphorylation
up-regulates
→
CREM
PSer277		phosphorylation
down-regulates
⊣		CREM11466319SIGNOR-275979
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CREMSIGNOR-275978
CDK1phosphorylation
→
down-regulates quantity 		CREMSIGNOR-276346
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CREMSIGNOR-275979