| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | CAV1 | Ser88 | FDGIWKAsFTTFTVT | phosphorylation unknown | 8058322 | SIGNOR-250835 |
| PTPN14 | CAV1 | – | dephosphorylation down-regulates activity | 32152405 | SIGNOR-277054 | |
| MET | CAV1 | – | phosphorylation up-regulates activity | 25148256 | SIGNOR-279080 | |
| FYN | CAV1 | Tyr14 | VDSEGHLyTVPIREQ | phosphorylation down-regulates activity | 12921535 | SIGNOR-118003 |
| SRC | CAV1 | Tyr14 | VDSEGHLyTVPIREQ | phosphorylation down-regulates activity | 12921535 | SIGNOR-118007 |
| PTPN1 | CAV1 | Tyr14 | VDSEGHLyTVPIREQ | dephosphorylation unknown | 16388599 | SIGNOR-248430 |
| CSNK2A2 | CAV1 | Ser88 | FDGIWKAsFTTFTVT | phosphorylation unknown | 8058322 | SIGNOR-250981 |
| EPHB1 | CAV1 | Tyr14 | VDSEGHLyTVPIREQ | phosphorylation down-regulates quantity by destabilization | 32238105 | SIGNOR-280008 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | CAV1 PSer88 | phosphorylation down-regulates ⊣ | CAV1 | 8058322 | SIGNOR-250835 |
| FYN | phosphorylation up-regulates → | CAV1 PTyr14 | phosphorylation down-regulates ⊣ | CAV1 | 12921535 | SIGNOR-118003 |
| SRC | phosphorylation up-regulates → | CAV1 PTyr14 | phosphorylation down-regulates ⊣ | CAV1 | 12921535 | SIGNOR-118007 |
| PTPN1 | dephosphorylation down-regulates ⊣ | CAV1 PTyr14 | dephosphorylation up-regulates → | CAV1 | 16388599 | SIGNOR-248430 |
| CSNK2A2 | phosphorylation up-regulates → | CAV1 PSer88 | phosphorylation down-regulates ⊣ | CAV1 | 8058322 | SIGNOR-250981 |
| EPHB1 | phosphorylation up-regulates → | CAV1 PTyr14 | phosphorylation down-regulates ⊣ | CAV1 | 32238105 | SIGNOR-280008 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation → unknown | CAV1 | SIGNOR-250835 |
| PTPN14 | dephosphorylation → down-regulates activity | CAV1 | SIGNOR-277054 |
| MET | phosphorylation → up-regulates activity | CAV1 | SIGNOR-279080 |
| FYN | phosphorylation → down-regulates activity | CAV1 | SIGNOR-118003 |
| SRC | phosphorylation → down-regulates activity | CAV1 | SIGNOR-118007 |
| PTPN1 | dephosphorylation → unknown | CAV1 | SIGNOR-248430 |
| CSNK2A2 | phosphorylation → unknown | CAV1 | SIGNOR-250981 |
| EPHB1 | phosphorylation down-regulates quantity by destabilization | CAV1 | SIGNOR-280008 |
