Entity Details

Name PTPN1_Tyr14
ID Q03135
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCCAV1Tyr14VDSEGHLyTVPIREQphosphorylation
down-regulates activity		12921535SIGNOR-118007
PTPN1CAV1Tyr14VDSEGHLyTVPIREQdephosphorylation
unknown		16388599SIGNOR-248430
EPHB1CAV1Tyr14VDSEGHLyTVPIREQphosphorylation
down-regulates quantity by destabilization		32238105SIGNOR-280008
FYNCAV1Tyr14VDSEGHLyTVPIREQphosphorylation
down-regulates activity		12921535SIGNOR-118003
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
CAV1
PTyr14		phosphorylation
down-regulates
⊣		CAV112921535SIGNOR-118007
PTPN1dephosphorylation
down-regulates
⊣
CAV1
PTyr14		dephosphorylation
up-regulates
→		CAV116388599SIGNOR-248430
EPHB1phosphorylation
up-regulates
→
CAV1
PTyr14		phosphorylation
down-regulates
⊣		CAV132238105SIGNOR-280008
FYNphosphorylation
up-regulates
→
CAV1
PTyr14		phosphorylation
down-regulates
⊣		CAV112921535SIGNOR-118003
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
down-regulates activity 		CAV1SIGNOR-118007
PTPN1dephosphorylation
→
unknown 		CAV1SIGNOR-248430
EPHB1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CAV1SIGNOR-280008
FYNphosphorylation
→
down-regulates activity 		CAV1SIGNOR-118003