| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | NOTCH2 | Ser2070 | DEYNVTPsPPGTVLT | phosphorylation down-regulates activity | 12794074 | SIGNOR-251254 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | NOTCH2 PSer2070 | phosphorylation down-regulates ⊣ | NOTCH2 | 12794074 | SIGNOR-251254 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation → down-regulates activity | NOTCH2 | SIGNOR-251254 |