Entity Details

Name GSK3B_Thr2074
ID Q04721
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BNOTCH2Thr2074VTPSPPGtVLTSALSphosphorylation
down-regulates activity		12794074SIGNOR-101574
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
NOTCH2
PThr2074		phosphorylation
down-regulates
⊣		NOTCH212794074SIGNOR-101574
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
→
down-regulates activity 		NOTCH2SIGNOR-101574