| Name | PRKCQ |
| ID | Q04759 |
| Role | substrate |
| Enzymatic Domains |
C2 1-107 PROSITE-ProRule
Protein kinase 380-634 PROSITE-ProRule
AGC-kinase C-terminal 635-706 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP4K3 | PRKCQ | Thr538 | LGDAKTNtFCGTPDY | phosphorylation up-regulates | 21983831 | SIGNOR-176744 |
| LCK | PRKCQ | Tyr90 | SETTVELySLAERCR | phosphorylation unknown | 10652356 | SIGNOR-74574 |
| FYN | PRKCQ | – | phosphorylation up-regulates | 10383400 | SIGNOR-68798 | |
| PRKCQ | PRKCQ | Thr219 | SAINSREtMFHKERF | phosphorylation up-regulates activity | 16252004 | SIGNOR-249298 |
| PDPK1 | PRKCQ | – | phosphorylation up-regulates | 15802604 | SIGNOR-134869 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP4K3 | phosphorylation up-regulates → | PRKCQ PThr538 | phosphorylation up-regulates → | PRKCQ | 21983831 | SIGNOR-176744 |
| LCK | phosphorylation up-regulates → | PRKCQ PTyr90 | phosphorylation down-regulates ⊣ | PRKCQ | 10652356 | SIGNOR-74574 |
| PRKCQ | phosphorylation up-regulates → | PRKCQ PThr219 | phosphorylation up-regulates → | PRKCQ | 16252004 | SIGNOR-249298 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAP4K3 | phosphorylation → up-regulates | PRKCQ | SIGNOR-176744 |
| LCK | phosphorylation → unknown | PRKCQ | SIGNOR-74574 |
| FYN | phosphorylation → up-regulates | PRKCQ | SIGNOR-68798 |
| PRKCQ | phosphorylation → up-regulates activity | PRKCQ | SIGNOR-249298 |
| PDPK1 | phosphorylation → up-regulates | PRKCQ | SIGNOR-134869 |