| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | UBE3A | Tyr659 | GDSHPVLyQSLKDLL | phosphorylation down-regulates activity | 23581475 | SIGNOR-260930 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | phosphorylation up-regulates → | UBE3A PTyr659 | phosphorylation down-regulates ⊣ | UBE3A | 23581475 | SIGNOR-260930 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ABL1 | phosphorylation → down-regulates activity | UBE3A | SIGNOR-260930 |