Entity Details

Name LRRK2_Thr474
ID Q05397
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LRRK2PTK2Thr474KFLQEALtMRQFDHPphosphorylation
down-regulates activity		26365310SIGNOR-278281
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LRRK2phosphorylation
up-regulates
→
PTK2
PThr474		phosphorylation
down-regulates
⊣		PTK226365310SIGNOR-278281
Regulator Mechanism/Effect Target SIGNOR-ID
LRRK2phosphorylation
→
down-regulates activity 		PTK2SIGNOR-278281