| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RET | PTK2 | Tyr925 | DRSNDKVyENVTGLV | phosphorylation up-regulates | 21454698 | SIGNOR-173021 |
| MET | PTK2 | Tyr925 | DRSNDKVyENVTGLV | phosphorylation up-regulates | 16782899 | SIGNOR-147203 |
| FGR | PTK2 | Tyr925 | DRSNDKVyENVTGLV | phosphorylation up-regulates | 12387730 | SIGNOR-94405 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RET | phosphorylation up-regulates → | PTK2 PTyr925 | phosphorylation up-regulates → | PTK2 | 21454698 | SIGNOR-173021 |
| MET | phosphorylation up-regulates → | PTK2 PTyr925 | phosphorylation up-regulates → | PTK2 | 16782899 | SIGNOR-147203 |
| FGR | phosphorylation up-regulates → | PTK2 PTyr925 | phosphorylation up-regulates → | PTK2 | 12387730 | SIGNOR-94405 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RET | phosphorylation → up-regulates | PTK2 | SIGNOR-173021 |
| MET | phosphorylation → up-regulates | PTK2 | SIGNOR-147203 |
| FGR | phosphorylation → up-regulates | PTK2 | SIGNOR-94405 |
