| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MET | PTK2 | Tyr407 | IIDEEDTyTMPSTRD | phosphorylation up-regulates | 16782899 | SIGNOR-147187 |
| PTK2 | PTK2 | Tyr407 | IIDEEDTyTMPSTRD | phosphorylation up-regulates | 15694384 | SIGNOR-133837 |
| PTK2B | PTK2 | Tyr407 | IIDEEDTyTMPSTRD | phosphorylation up-regulates | 16760434 | SIGNOR-147070 |
| SRC | PTK2 | Tyr407 | IIDEEDTyTMPSTRD | phosphorylation up-regulates | 15735019 | SIGNOR-150480 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MET | phosphorylation up-regulates → | PTK2 PTyr407 | phosphorylation up-regulates → | PTK2 | 16782899 | SIGNOR-147187 |
| PTK2 | phosphorylation up-regulates → | PTK2 PTyr407 | phosphorylation up-regulates → | PTK2 | 15694384 | SIGNOR-133837 |
| PTK2B | phosphorylation up-regulates → | PTK2 PTyr407 | phosphorylation up-regulates → | PTK2 | 16760434 | SIGNOR-147070 |
| SRC | phosphorylation up-regulates → | PTK2 PTyr407 | phosphorylation up-regulates → | PTK2 | 15735019 | SIGNOR-150480 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MET | phosphorylation → up-regulates | PTK2 | SIGNOR-147187 |
| PTK2 | phosphorylation → up-regulates | PTK2 | SIGNOR-133837 |
| PTK2B | phosphorylation → up-regulates | PTK2 | SIGNOR-147070 |
| SRC | phosphorylation → up-regulates | PTK2 | SIGNOR-150480 |
