| Name | ZBTB16 |
| ID | Q05516 |
| Role | substrate |
| Enzymatic Domains |
BTB 34-96 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | ZBTB16 | Ser197 | SFGLSAMsPTKAAVD | phosphorylation down-regulates | 18246121 | SIGNOR-160626 |
| CDK2 | ZBTB16 | Thr282 | RGKEGPGtPTRSSVI | phosphorylation down-regulates | 18246121 | SIGNOR-160630 |
| GSK3B | ZBTB16 | Thr282 | RGKEGPGtPTRSSVI | phosphorylation up-regulates activity | 25821988 | SIGNOR-279618 |
| GSK3B | ZBTB16 | Ser184 | PGPMVDQsPSVSTSF | phosphorylation up-regulates activity | 25821988 | SIGNOR-279619 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | ZBTB16 PSer197 | phosphorylation down-regulates ⊣ | ZBTB16 | 18246121 | SIGNOR-160626 |
| CDK2 | phosphorylation up-regulates → | ZBTB16 PThr282 | phosphorylation down-regulates ⊣ | ZBTB16 | 18246121 | SIGNOR-160630 |
| GSK3B | phosphorylation up-regulates → | ZBTB16 PThr282 | phosphorylation up-regulates → | ZBTB16 | 25821988 | SIGNOR-279618 |
| GSK3B | phosphorylation up-regulates → | ZBTB16 PSer184 | phosphorylation up-regulates → | ZBTB16 | 25821988 | SIGNOR-279619 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation down-regulates | ZBTB16 | SIGNOR-160626 |
| CDK2 | phosphorylation down-regulates | ZBTB16 | SIGNOR-160630 |
| GSK3B | phosphorylation → up-regulates activity | ZBTB16 | SIGNOR-279618 |
| GSK3B | phosphorylation → up-regulates activity | ZBTB16 | SIGNOR-279619 |