| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | ZBTB16 | Thr282 | RGKEGPGtPTRSSVI | phosphorylation up-regulates activity | 25821988 | SIGNOR-279618 |
| CDK2 | ZBTB16 | Thr282 | RGKEGPGtPTRSSVI | phosphorylation down-regulates | 18246121 | SIGNOR-160630 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | ZBTB16 PThr282 | phosphorylation up-regulates → | ZBTB16 | 25821988 | SIGNOR-279618 |
| CDK2 | phosphorylation up-regulates → | ZBTB16 PThr282 | phosphorylation down-regulates ⊣ | ZBTB16 | 18246121 | SIGNOR-160630 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation → up-regulates activity | ZBTB16 | SIGNOR-279618 |
| CDK2 | phosphorylation down-regulates | ZBTB16 | SIGNOR-160630 |
