Entity Details

Name DUSP2
ID Q05923
Role phosphatase
Enzymatic Domains
Rhodanese 23-144
PROSITE-ProRule
Tyrosine-protein phosphatase 172-313
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
DUSP2MAPK1–dephosphorylation
down-regulates		8626452SIGNOR-40915
DUSP2MAPK4–dephosphorylation
down-regulates activity		28252035SIGNOR-277068
DUSP2MAPK14–dephosphorylation
down-regulates		8626452SIGNOR-40918
DUSP2MAPK6–dephosphorylation
down-regulates activity		28252035SIGNOR-277069
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
Regulator Mechanism/Effect Target SIGNOR-ID
DUSP2dephosphorylation
img/direct_inhibition.png
down-regulates 		MAPK1SIGNOR-40915
DUSP2dephosphorylation
→
down-regulates activity 		MAPK4SIGNOR-277068
DUSP2dephosphorylation
img/direct_inhibition.png
down-regulates 		MAPK14SIGNOR-40918
DUSP2dephosphorylation
→
down-regulates activity 		MAPK6SIGNOR-277069