| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | BTK | Thr495 | EMRHRFQtQQLLEMC | phosphorylation down-regulates quantity by destabilization | 23754751 | SIGNOR-276465 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | BTK PThr495 | phosphorylation down-regulates ⊣ | BTK | 23754751 | SIGNOR-276465 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation down-regulates quantity by destabilization | BTK | SIGNOR-276465 |
