| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | BTK | Ser180 | GSLKPGSsHRKTKKP | phosphorylation down-regulates activity | 11598012 | SIGNOR-249110 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | phosphorylation up-regulates → | BTK PSer180 | phosphorylation down-regulates ⊣ | BTK | 11598012 | SIGNOR-249110 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCB | phosphorylation → down-regulates activity | BTK | SIGNOR-249110 |