Entity Details

Name SYK_Tyr551
ID Q06187
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCBTKTyr551RYVLDDEyTSSVGSKphosphorylation
up-regulates activity		8629002SIGNOR-251100
BTKBTKTyr551RYVLDDEyTSSVGSKphosphorylation
up-regulates		8630736SIGNOR-41480
LYNBTKTyr551RYVLDDEyTSSVGSKphosphorylation
up-regulates		8630736SIGNOR-41607
SYKBTKTyr551RYVLDDEyTSSVGSKphosphorylation
up-regulates activity		11226282SIGNOR-247586
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
BTK
PTyr551		phosphorylation
up-regulates
→		BTK8629002SIGNOR-251100
BTKphosphorylation
up-regulates
→
BTK
PTyr551		phosphorylation
up-regulates
→		BTK8630736SIGNOR-41480
LYNphosphorylation
up-regulates
→
BTK
PTyr551		phosphorylation
up-regulates
→		BTK8630736SIGNOR-41607
SYKphosphorylation
up-regulates
→
BTK
PTyr551		phosphorylation
up-regulates
→		BTK11226282SIGNOR-247586
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		BTKSIGNOR-251100
BTKphosphorylation
→
up-regulates 		BTKSIGNOR-41480
LYNphosphorylation
→
up-regulates 		BTKSIGNOR-41607
SYKphosphorylation
→
up-regulates activity 		BTKSIGNOR-247586