| Name | GFPT1 |
| ID | Q06210 |
| Role | substrate |
| Enzymatic Domains |
Glutamine amidotransferase type-2 2-305 PROSITE-ProRule
SIS 1 377-516 PROSITE-ProRule
SIS 2 548-689 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKAA1 | GFPT1 | Ser242 | SKFTRWGsQGERGKD | phosphorylation down-regulates | 19170765 | SIGNOR-183528 |
| PRKAA1 | GFPT1 | Ser261 | CNLSRVDsTTCLFPV | phosphorylation up-regulates | 17941647 | SIGNOR-158490 |
| PRKCA | GFPT1 | Ser205 | AVGTRRGsPLLIGVR | phosphorylation down-regulates activity | 10806197 | SIGNOR-249040 |
| CAMK2A | GFPT1 | Ser261 | CNLSRVDsTTCLFPV | phosphorylation up-regulates | 17941647 | SIGNOR-158486 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKAA1 | phosphorylation up-regulates → | GFPT1 PSer242 | phosphorylation down-regulates ⊣ | GFPT1 | 19170765 | SIGNOR-183528 |
| PRKAA1 | phosphorylation up-regulates → | GFPT1 PSer261 | phosphorylation up-regulates → | GFPT1 | 17941647 | SIGNOR-158490 |
| PRKCA | phosphorylation up-regulates → | GFPT1 PSer205 | phosphorylation down-regulates ⊣ | GFPT1 | 10806197 | SIGNOR-249040 |
| CAMK2A | phosphorylation up-regulates → | GFPT1 PSer261 | phosphorylation up-regulates → | GFPT1 | 17941647 | SIGNOR-158486 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKAA1 | phosphorylation down-regulates | GFPT1 | SIGNOR-183528 |
| PRKAA1 | phosphorylation → up-regulates | GFPT1 | SIGNOR-158490 |
| PRKCA | phosphorylation → down-regulates activity | GFPT1 | SIGNOR-249040 |
| CAMK2A | phosphorylation → up-regulates | GFPT1 | SIGNOR-158486 |