| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | ZFP36L1 | Ser92 | RFRDRSFsEGGERLL | phosphorylation down-regulates | 15538381 | SIGNOR-130376 |
| MAPKAPK2 | ZFP36L1 | Ser54 | GGFPRRHsVTLPSSK | phosphorylation down-regulates | 18326031 | SIGNOR-161274 |
| MAPKAPK2 | ZFP36L1 | Ser92 | RFRDRSFsEGGERLL | phosphorylation down-regulates | 18326031 | SIGNOR-161278 |
| AKT | ZFP36L1 | Ser92 | RFRDRSFsEGGERLL | phosphorylation down-regulates | 15538381 | SIGNOR-244385 |
| RPS6KA1 | ZFP36L1 | – | phosphorylation down-regulates activity | 25106868 | SIGNOR-279280 | |
| MAPKAPK2 | ZFP36L1 | Ser203 | PRLQHSFsFAGFPSA | phosphorylation down-regulates | 18326031 | SIGNOR-161270 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | ZFP36L1 PSer92 | phosphorylation down-regulates ⊣ | ZFP36L1 | 15538381 | SIGNOR-130376 |
| MAPKAPK2 | phosphorylation up-regulates → | ZFP36L1 PSer54 | phosphorylation down-regulates ⊣ | ZFP36L1 | 18326031 | SIGNOR-161274 |
| MAPKAPK2 | phosphorylation up-regulates → | ZFP36L1 PSer92 | phosphorylation down-regulates ⊣ | ZFP36L1 | 18326031 | SIGNOR-161278 |
| AKT | phosphorylation up-regulates → | ZFP36L1 PSer92 | phosphorylation down-regulates ⊣ | ZFP36L1 | 15538381 | SIGNOR-244385 |
| MAPKAPK2 | phosphorylation up-regulates → | ZFP36L1 PSer203 | phosphorylation down-regulates ⊣ | ZFP36L1 | 18326031 | SIGNOR-161270 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation![]() down-regulates | ZFP36L1 | SIGNOR-130376 |
| MAPKAPK2 | phosphorylation![]() down-regulates | ZFP36L1 | SIGNOR-161274 |
| MAPKAPK2 | phosphorylation![]() down-regulates | ZFP36L1 | SIGNOR-161278 |
| AKT | phosphorylation![]() down-regulates | ZFP36L1 | SIGNOR-244385 |
| RPS6KA1 | phosphorylation → down-regulates activity | ZFP36L1 | SIGNOR-279280 |
| MAPKAPK2 | phosphorylation![]() down-regulates | ZFP36L1 | SIGNOR-161270 |