Entity Details

Name BAX
ID Q07812
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1BAXSer184VAGVLTAsLTIWKKMphosphorylation
down-regulates activity		14766748SIGNOR-252538
PRKCZBAXSer184VAGVLTAsLTIWKKMphosphorylation
down-regulates activity		17525161SIGNOR-155111
GSK3BBAXSer163GGWDGLLsYFGTPTWphosphorylation
up-regulates		15525785SIGNOR-130141
AKTBAXSer184VAGVLTAsLTIWKKMphosphorylation
down-regulates activity		14766748SIGNOR-209651
PPM1DBAX–dephosphorylation
down-regulates activity		23907458SIGNOR-276993
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
BAX
PSer184		phosphorylation
down-regulates
⊣		BAX14766748SIGNOR-252538
PRKCZphosphorylation
up-regulates
→
BAX
PSer184		phosphorylation
down-regulates
⊣		BAX17525161SIGNOR-155111
GSK3Bphosphorylation
up-regulates
→
BAX
PSer163		phosphorylation
up-regulates
→		BAX15525785SIGNOR-130141
AKTphosphorylation
up-regulates
→
BAX
PSer184		phosphorylation
down-regulates
⊣		BAX14766748SIGNOR-209651
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
down-regulates activity 		BAXSIGNOR-252538
PRKCZphosphorylation
→
down-regulates activity 		BAXSIGNOR-155111
GSK3Bphosphorylation
→
up-regulates 		BAXSIGNOR-130141
AKTphosphorylation
→
down-regulates activity 		BAXSIGNOR-209651
PPM1Ddephosphorylation
→
down-regulates activity 		BAXSIGNOR-276993