| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | FOXM1 | Thr611 | ETLPISStPSKSVLP | phosphorylation up-regulates | 19737929 | SIGNOR-216837 |
| CDK2 | FOXM1 | Thr611 | ETLPISStPSKSVLP | phosphorylation up-regulates activity | 15024056 | SIGNOR-250731 |
| CDK1 | FOXM1 | Thr611 | ETLPISStPSKSVLP | phosphorylation up-regulates | 19737929 | SIGNOR-187880 |
| CDK4 | FOXM1 | Thr611 | ETLPISStPSKSVLP | phosphorylation up-regulates | 22094256 | SIGNOR-177255 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | FOXM1 PThr611 | phosphorylation up-regulates → | FOXM1 | 19737929 | SIGNOR-216837 |
| CDK2 | phosphorylation up-regulates → | FOXM1 PThr611 | phosphorylation up-regulates → | FOXM1 | 15024056 | SIGNOR-250731 |
| CDK1 | phosphorylation up-regulates → | FOXM1 PThr611 | phosphorylation up-regulates → | FOXM1 | 19737929 | SIGNOR-187880 |
| CDK4 | phosphorylation up-regulates → | FOXM1 PThr611 | phosphorylation up-regulates → | FOXM1 | 22094256 | SIGNOR-177255 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation → up-regulates | FOXM1 | SIGNOR-216837 |
| CDK2 | phosphorylation → up-regulates activity | FOXM1 | SIGNOR-250731 |
| CDK1 | phosphorylation → up-regulates | FOXM1 | SIGNOR-187880 |
| CDK4 | phosphorylation → up-regulates | FOXM1 | SIGNOR-177255 |
